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1

New Novobiocin Analogues as Antiproliferative Agents in Breast Cancer Cells and Potential Inhibitors of Heat Shock Protein 90

Le Bras, Gaëlle, Radanyi, Christine, Peyrat, Jean-François, Brion, Jean-Daniel, Alami, Mouâd, Marsaud, Véronique, Stella, Barbara, Renoir, Jack-Michel

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 383 KB

english, 2007

2

Estrogen receptor signaling as a target for novel breast cancer therapeutics

Renoir, Jack-Michel, Marsaud, Véronique, Lazennec, Gwendal

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.34 MB

english, 2013

3

Lipoplexes Targeting the CD44 Hyaluronic Acid Receptor for Efficient Transfection of Breast Cancer Cells

Surace, Claudio, Arpicco, Silvia, Dufaÿ-Wojcicki, Amélie, Marsaud, Véronique, Bouclier, Céline, Clay, Denis, Cattel, Luigi, Renoir, Jack-Michel, Fattal, Elias

Journal:

Molecular Pharmaceutics

Year:

2009

Language:

english

File:

PDF, 2.91 MB

english, 2009

4

Anti-Estrogen-Loaded Superparamagnetic Liposomes for Intracellular Magnetic Targeting and Treatment of Breast Cancer Tumors

Vincent Plassat, Claire Wilhelm, Véronique Marsaud, Christine Ménager, Florence Gazeau, Jack-Michel Renoir, Sylviane Lesieur

Journal:

Advanced Functional Materials

Year:

2011

Language:

english

File:

PDF, 830 KB

english, 2011

5

Discovery and Biological Activity of 6BrCaQ as an Inhibitor of the Hsp90 Protein Folding Machinery

Dr. Davide Audisio, Dr. Samir Messaoudi, Lukasz Cegielkowski, Prof. Jean-François Peyrat, Prof. Jean-Daniel Brion, Dr. Délphine Methy-Gonnot, Dr. Christine Radanyi, Dr. Jack-Michel Renoir, Dr. Mouâd A

Journal:

Year:

2011

Language:

english

File:

PDF, 607 KB

english, 2011

6

Cover Picture: Discovery and Biological Activity of 6BrCaQ as an Inhibitor of the Hsp90 Protein Folding Machinery (ChemMedChem 5/2011)

Dr. Davide Audisio, Dr. Samir Messaoudi, Lukasz Cegielkowski, Prof. Jean-François Peyrat, Prof. Jean-Daniel Brion, Dr. Délphine Methy-Gonnot, Dr. Christine Radanyi, Dr. Jack-Michel Renoir, Dr. Mouâd A

Journal:

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

7

In vitro and in vivo biologic evaluation of long-circulating biodegradable drug carriers loaded with the pure antiestrogen RU 58668

Thibault Ameller, Véronique Marsaud, Philippe Legrand, Ruxandra Gref, Jack-Michel Renoir

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 511 KB

english, 2003

8

Pure antiestrogen-induced G1-arrest in myeloma cells results from the reduced kinase activity of cyclin D3/CDK6 complexes whereas apoptosis is mediated by endoplasmic reticulum-dependent caspases

Juliette Gauduchon, Amélie Seguin, Véronique Marsaud, Denis Clay, Jack-Michel Renoir, Brigitte Sola

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 908 KB

english, 2008

9

Encapsulation of gemcitabine lipophilic derivatives into polycyanoacrylate nanospheres and nanocapsules

Barbara Stella, Silvia Arpicco, Flavio Rocco, Véronique Marsaud, Jack-Michel Renoir, Luigi Cattel, Patrick Couvreur

Journal:

International Journal of Pharmaceutics

Year:

2007

Language:

english

File:

PDF, 248 KB

english, 2007

10

Nanoparticles loaded with ferrocenyl tamoxifen derivatives for breast cancer treatment

Anh Nguyen, Véronique Marsaud, Céline Bouclier, Siden Top, Anne Vessieres, Pascal Pigeon, Ruxandra Gref, Philippe Legrand, Gérard Jaouen, Jack-Michel Renoir

Journal:

International Journal of Pharmaceutics

Year:

2008

Language:

english

File:

PDF, 499 KB

english, 2008

11

Liposomes loaded with histone deacetylase inhibitors for breast cancer therapy

Giorgia Urbinati, Véronique Marsaud, Vincent Plassat, Elias Fattal, Sylviane Lesieur, Jack-Michel Renoir

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 825 KB

english, 2010

12

Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90)

Christine Radanyi, Gaëlle Le Bras, Samir Messaoudi, Céline Bouclier, Jean-François Peyrat, Jean-Daniel Brion, Véronique Marsaud, Jack-Michel Renoir, Mouâd Alami

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 178 KB

english, 2008

13

β-Amyloid efflux mediated by p-glycoprotein

Fred C. Lam, Ronghua Liu, Peihua Lu, Adam B. Shapiro, Jack-Michel Renoir, Frances J. Sharom, Peter B. Reiner

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 579 KB

english, 2001

14

Coadministration of nanosystems of short silencing RNAs targeting oestrogen receptor α and anti-oestrogen synergistically induces tumour growth inhibition in human breast cancer xenografts

Céline Bouclier, Véronique Marsaud, Olivia Bawa, Valérie Nicolas, Laurence Moine, Paule Opolon, Jack-Michel Renoir

Journal:

Breast Cancer Research and Treatment

Year:

2010

Language:

english

File:

PDF, 1.23 MB

english, 2010

15

Therapeutic Potential of New 4-hydroxy-tamoxifen-Loaded pH-gradient Liposomes in a Multiple Myeloma Experimental Model

Giorgia Urbinati, Davide Audisio, Véronique Marsaud, Vincent Plassat, Silvia Arpicco, Brigitte Sola, Elias Fattal, Jack-Michel Renoir

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 355 KB

english, 2010

16

Pure antiestrogen RU 58668—loaded nanospheres: morphology, cell activity and toxicity studies

Thibault Ameller, Véronique Marsaud, Philippe Legrand, Ruxandra Gref, Jack-Michel Renoir

Journal:

European Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 517 KB

english, 2004

17

Alternative cyclin D1 forms a and b have different biological functions in the cell cycle of B lymphocytes

Céline Lévêque, Véronique Marsaud, Jack-Michel Renoir, Brigitte Sola

Journal:

Experimental Cell Research

Year:

2007

Language:

english

File:

PDF, 1.51 MB

english, 2007

18

Progesterone Receptor from Chick Oviduct: : Purification of Molybdate-Stabilized Form and Preliminary Characterization

Jack-Michel RENOIR, Chang-Ren YANG, Pierre FORMSTECHER, Patrick LUSTENBERGER, Adèle WOLFSON, Gérard REDEUILH, Jan MESTER, Hélène RICHARD-FOY, Etienne-Emile BAULIEU

Journal:

Year:

1982

Language:

english

File:

PDF, 983 KB

english, 1982

19

Antibodies against Progesterone Receptor from Chick Oviduct : Cross-Reactivity with Mammalian Progesterone Receptors

Jack-Michel RENOIR, Christine RADANYI, Chang-Ren YANG, Etienne-Emile BAULIEU

Journal:

Year:

1982

Language:

english

File:

PDF, 572 KB

english, 1982

20

Chick oviduct glucocorticosteroid receptor : Specific binding of the synthetic steroid RU 486 and immunological studies with antibodies to chick oviduct progesterone receptor

André GROYER, Yves LE BOUC, Irène JOAB, Christine RADANYI, Jack-Michel RENOIR, Paul ROBEL, Etienne-Emile BAULIEU

Journal:

Year:

1985

Language:

english

File:

PDF, 745 KB

english, 1985

21

Effects of urea and molybdate on the chick oviduct progesterone receptor

Thierry Buchou, Jan Mester, Jack-Michel Renoir, Etienne-Emile Baulieu

Journal:

Biochemical and Biophysical Research Communications

Year:

1983

Language:

english

File:

PDF, 532 KB

english, 1983

22

Protein kinase activity of purified components of the chicken oviduct progesterone receptor

Teresa Garcia, Pentti Tuohimaa, Jan Mester, Thierry Buchou, Jack-Michel Renoir, Etienne-Emile Baulieu

Journal:

Biochemical and Biophysical Research Communications

Year:

1983

Language:

english

File:

PDF, 1.41 MB

english, 1983

23

Rabbit FKBP59-heat shock protein binding immunophillin (HBI) is a calmodulin binding protein

Nelly Massol, Marie-Claire Lebeau, Jack-Michel Renoir, Lee E. Faber, Etienne-Emile Baulieu

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 988 KB

english, 1992

24

Nuclear localization of two steroid receptor-associated proteins, hsp90 and p59

Jean-Marie Gasc, Jack-Michel Renoir, Lee E. Faber, Francine Delahaye, Etienne-Emile Baulieu

Journal:

Experimental Cell Research

Year:

1990

Language:

english

File:

PDF, 1.53 MB

english, 1990

25

An antiserum specific for human sex steroid-binding plasma protein (SBP)

Jack-Michel Renoir, Linda L. Fox, Etienne-Emile Baulieu, Christine Mercier-Bodard

Journal:

Year:

1977

Language:

english

File:

PDF, 909 KB

english, 1977

26

Further characterization and immunological studies of human sex steroid binding plasma protein

Christine Mercier-Bodard, Jack-Michel Renoir, Etienne-Emile Baulieu

Journal:

Journal of Steroid Biochemistry

Year:

1979

Language:

english

File:

PDF, 622 KB

english, 1979

27

Chick oviduct progesterone receptor phosphorylation: Characterization of a copurified kinase and phosphorylation in primary cultures

Teresa Garcia, Thierry Buchou, Ingrid Jung-Testas, Jack-Michel Renoir, Etienne Emile Baulieu

Journal:

Journal of Steroid Biochemistry

Year:

1987

Language:

english

File:

PDF, 801 KB

english, 1987

28

The antiprogesterone RU486 stabilizes the heterooligomeric, non-DNA-binding, 8S-form of the rabbit uterus cytosol progesterone receptor

Jack-Michel Renoir, Christine Radanyi, Etienne-Emile Baulieu

Journal:

Year:

1989

Language:

english

File:

PDF, 769 KB

english, 1989

29

Tosylcyclonovobiocic acids promote cleavage of the hsp90-associated cochaperone p23

Christine Radanyi, Gaëlle Le Bras, Céline Bouclier, Samir Messaoudi, Jean-François Peyrat, Jean-Daniel Brion, Mouâd Alami, Jack-Michel Renoir

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 720 KB

english, 2009

30

Antiproliferative and apoptotic activities of tosylcyclonovobiocic acids as potent heat shock protein 90 inhibitors in human cancer cells

Christine Radanyi, Gaëlle Le Bras, Véronique Marsaud, Jean-François Peyrat, Samir Messaoudi, Maria-Grazia Catelli, Jean-Daniel Brion, Mouâd Alami, Jack-Michel Renoir

Journal:

Year:

2009

Language:

english

File:

PDF, 400 KB

english, 2009

31

Drug delivery systems for oestrogenic hormones and antagonists: the need for selective targeting in estradiol-dependent cancers

Thibault Ameller, Philippe Legrand, Véronique Marsaud, Jack-Michel Renoir

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 321 KB

english, 2004

32

Estrogen receptor α and β subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells

Angélique Gougelet, Céline Bouclier, Véronique Marsaud, Sébastien Maillard, Stefan O. Mueller, Kenneth S. Korach, Jack-Michel Renoir

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 521 KB

english, 2005

33

Innovative drug delivery nanosystems improve the anti-tumor activity in vitro and in vivo of anti-estrogens in human breast cancer and multiple myeloma

Sébastien Maillard, Thibault Ameller, Juliette Gauduchon, Angélique Gougelet, Fabrice Gouilleux, Philippe Legrand, Véronique Marsaud, Elias Fattal, Brigitte Sola, Jack-Michel Renoir

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 377 KB

english, 2005

34

Improved antitumoral properties of pure antiestrogen RU 58668-loaded liposomes in multiple myeloma

Sébastien Maillard, Juliette Gauduchon, Véronique Marsaud, Fabrice Gouilleux, Elisabeth Connault, Paule Opolon, Elias Fattal, Brigitte Sola, Jack-Michel Renoir

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 586 KB

english, 2006

35

Improved anti-tumoral capacity of mixed and pure anti-oestrogens in breast cancer cell xenografts after their administration by entrapment in colloidal nanosystems

Jack-Michel Renoir, Barbara Stella, Thibault Ameller, Elisabeth Connault, Paule Opolon, Véronique Marsaud

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 1.91 MB

english, 2006

36

Oestrogen receptors pathways to oestrogen responsive elements: The transactivation function-1 acts as the keystone of oestrogen receptor (ER)β-mediated transcriptional repression of ERα

Angélique Gougelet, Stefan O. Mueller, Ken S. Korach, Jack-Michel Renoir

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 853 KB

english, 2007

37

Antibodies against highly purified b-subunit of the chick oviduct progesterone receptor

Pentti Tuohimaa, Jack-Michel Renoir, Christine Radanyi, Jan Mester, Irène Joab, Thierry Buchou, Etienne-Emile Baulieu

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 463 KB

english, 1984

38

Dexamethasone and triamcinolone acetonide accumulation in mouse fibroblasts is differently modulated by the immunosuppressants cyclosporin A, FK506, rapamycin and their analogues, as well as by other P-glycoprotein ligands

Véronique Marsaud, Christine Mercier-Bodard, Dominique Fortin, Stéphane Le Bihan, Jack-Michel Renoir

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1998

Language:

english

File:

PDF, 565 KB

english, 1998

39

Estradiol receptors in breast cancer cells: Associated co-factors as targets for new therapeutic approaches

Jack-Michel Renoir

Journal:

Year:

2012

Language:

english

File:

PDF, 792 KB

english, 2012

40

Estrogenic or antiestrogenic therapies for multiple myeloma?

Brigitte Sola, Jack-Michel Renoir

Journal:

Molecular Cancer

Year:

2007

Language:

english

File:

PDF, 611 KB

english, 2007

41

Cyclin K and cyclin D1b are oncogenic in myeloma cells

Véronique Marsaud, Guergana Tchakarska, Geoffroy Andrieux, Jian-Miao Liu, Doulaye Dembele, Bernard Jost, Joanna Wdzieczak-Bakala, Jack-Michel Renoir, Brigitte Sola

Journal:

Molecular Cancer

Year:

2010

Language:

english

File:

PDF, 2.53 MB

english, 2010

42

Anticancer Efficacy of Squalenoyl Gemcitabine Nanomedicine on 60 Human Tumor Cell Panel and on Experimental Tumor

Reddy, L. Harivardhan, Renoir, Jack-Michel, Marsaud, Veronique, Lepetre-Mouelhi, Sinda, Desmaële, Didier, Couvreur, Patrick

Journal:

Molecular Pharmaceutics

Year:

2009

Language:

english

File:

PDF, 1.87 MB

english, 2009

43

Hyaluronic Acid-Modified DOTAP/DOPE Liposomes for the Targeted Delivery of Anti-Telomerase siRNA to CD44-Expressing Lung Cancer Cells

Taetz, Sebastian, Bochot, Amélie, Surace, Claudio, Arpicco, Silvia, Renoir, Jack-Michel, Schaefer, Ulrich F., Marsaud, Véronique, Kerdine-Roemer, Saadia, Lehr, Claus-Michael, Fattal, Elias

Journal:

Oligonucleotides

Year:

2009

Language:

english

File:

PDF, 494 KB

english, 2009

44

Binding of Steroid Modulators to Recombinant Cytosolic Domain from Mouse P-Glycoprotein in Close Proximity to the ATP Site †

Dayan, Guila, Jault, Jean-Michel, Baubichon-Cortay, Hélène, Baggetto, Loris G., Renoir, Jack-Michel, Baulieu, Etienne-Emile, Gros, Philippe, Di Pietro, Attilio

Journal:

Year:

1997

Language:

english

File:

PDF, 236 KB

english, 1997

45

Effects of immunosuppressants FK506 and rapamycin on the heterooligomeric form of the progesterone receptor

Renoir, Jack-Michel, Le Bihan, Stéphane, Mercier-Bodard, Christine, Gold, Alex, Arjomandi, Merhdad, Radanyi, Christine, Baulieu, Etienne-Emile

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1994

Language:

english

File:

PDF, 1.02 MB

english, 1994

46

Immunosuppressants and Calcium/Calmodulin kinase(s) inhibitors modulate similarly glucocorticosteroid- and progestin-induced transcription.

Jack-Michel, Renoir, Véronique, Marsaud, Stéphane, Bihan, Christine, Mercier-Bodard, Etienne-Emile, Baulieu

Journal:

Biology of the Cell

Year:

1996

Language:

english

File:

PDF, 176 KB

english, 1996

47

Chick oviduct progesterone receptor: structure, immunology, function

Renoir, Jack-Michel, Mester, Jan

Journal:

Molecular and Cellular Endocrinology

Year:

1984

Language:

english

File:

PDF, 1.28 MB

english, 1984

48

A novel monoclonal anti-rabbit hsp90 antibody: Usefulness for studies on hsp90-steroid receptor interaction

Radanyi, Christine, Lombès, Marc, Renoir, Jack-Michel, Delahaye, Francine, Baulieu, Etienne-Emile

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1992

Language:

english

File:

PDF, 1.67 MB

english, 1992

49

[Part 1: Biological Sciences] || Monoclonal Antibody to Chicken Oviduct Progesterone Receptor

Christine Radanyi, Irene Joab, Jack-Michel Renoir, Helene Richard-Foy and Etienne-Emile Baulieu

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 771 KB

english, 1983

50

Receptors for Glucocorticosteroid and Progesterone Recognize Distinct Features of a DNA Regulatory Element

Dietmar Von Der Ahe, Jack-Michel Renoir, Thierry Buchou, Etienne-Emile Baulieu and Miguel Beato

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.20 MB

english, 1986